Fig. 6

Clinical utility evaluation of the radiomic signature and the radiomic nomogram using DCA curves. Evaluation in the training cohort (a), external validation cohort 1 (b), and external validation cohort 2 (c). The y-axis shows the net benefit. The x-axis shows the threshold probability. The highest net benefit was gained using the radiomic nomogram (red line) compared with the radiomic signature (blue line), the treat-all strategy (gray line), and the treat-none strategy (horizontal black line)