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Parameters
|
ER
|
p value
|
PR
|
p value
|
HER2
|
p value
|
Ki67
|
p value
|
|---|
|
Positive
|
Negative
|
Positive
|
Negative
|
Positive
|
Negative
|
High-proliferation
|
Low-proliferation
|
|---|
|
Arterial phase NIC
|
0.109 ± 0.067
|
0.133 ± 0.055
|
0.069
|
0.101 ± 0.063
|
0.128 ± 0.064
|
0.022
|
0.114 ± 0.058
|
0.117 ± 0.069
|
0.850
|
0.130 ± 0.063
|
0.096 ± 0.064
|
0.005
|
|
Venous phase NIC
|
0.336 ± 0.143
|
0.411 ± 0.133
|
0.003
|
0.317 ± 0.138
|
0.388 ± 0.133
|
0.005
|
0.381 ± 0.120
|
0.342 ± 0.149
|
0.138
|
0.409 ± 0.129
|
0.283 ± 0.120
|
<0.001
|
|
Arterial phase nZeff
|
0.72 ± 0.04
|
0.73 ± 0.04
|
0.164
|
0.72 ± 0.03
|
0.73 ± 0.04
|
0.437
|
0.73 ± 0.03
|
0.72 ± 0.05
|
0.077
|
0.74 ± 0.03
|
0.71 ± 0.05
|
<0.001
|
|
Venous phase nZeff
|
0.86 ± 0.06
|
0.88 ± 0.03
|
0.011
|
0.86 ± 0.06
|
0.87 ± 0.04
|
0.425
|
0.88 ± 0.03
|
0.86 ± 0.06
|
0.022
|
0.88 ± 0.04
|
0.85 ± 0.06
|
<0.001
|
|
Arterial phase λHu (HU/keV)
|
1.71 ± 0.84
|
1.94 ± 0.88
|
0.181
|
1.64 ± 0.85
|
1.88 ± 0.84
|
0.127
|
1.86 ± 0.76
|
1.72 ± 0.90
|
0.358
|
1.87 ± 0.96
|
1.64 ± 0.67
|
0.129
|
|
Venous phase λHu (HU/keV)
|
2.63 ± 0.98
|
2.75 ± 1.01
|
0.567
|
2.64 ± 0.85
|
2.68 ± 0.98
|
0.848
|
2.79 ± 0.95
|
2.58 ± 1.01
|
0.252
|
2.72 ± 1.10
|
2.58 ± 0.81
|
0.421
|
- Note—NIC normalized iodine concentration; nZeff normalized effective atomic number; λHu slope of the spectral Hounsfield unit curve; HU hounsfield unit; ER estrogen receptor; PR progesterone receptor; HER2 human epidermal growth factor receptor 2